Facts About Glutathione and Parkinson's Disease

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 How Death Occurs Due to Parkinson's Disease

It is a slowly progressive nervous system disorder that causes the progressive destruction of brain cells (neurons) in an area of ​​the brain called the substantia nigral. Death is usually due to secondary complications such as infection. 

One of the well-known mechanisms of neuronal destruction is damage from free radicals, or reactive oxygen species - destructive molecules formed as a result of the oxidation of the neurotransmitter dopamine. 



Role of Dopamine 

Cells in the substantia nigral use dopamine - a chemical messenger between brain or nerve cells - to communicate with cells in another area of ​​the brain called the striatum. 

With cell loss of the nigral, the dopamine levels of the nigral decrease, resulting in a decrease in dopamine in the striatum.

Most dopaminergic drugs used to treat Parkinson's disease are designed to temporarily supplement or mimic dopamine. They improve some symptoms, but they don't restore normal brain function or stop brain cell destruction. 

They cause serious side effects because they overstimulate nerve cells in other parts of the body, causing disorientation, hallucinations, nausea, and shaky limbs. 

The role of antioxidants 

The main free radical scavenger in cells of the substantia nigral is the powerful antioxidant glutathione injections in the brain. Glutathione levels in Parkinson's patients are low.

 At least 80% of the cells of the substantia nigral are lost before symptoms of Parkinson's disease appear. It is therefore essential to protect or maintain these cells under conditions of oxidative stress. 

How glutathione helps in Parkinson's disease:

Here are several factors below

  • Glutathione increases the brain's sensitivity to dopamine. So while glutathione doesn't increase dopamine levels, it does allow dopamine in the brain to work more efficiently. 
  • Glutathione's powerful antioxidant properties protect the brain from free radical damage. 
  • An even more intriguing benefit of glutathione is its powerful detoxifying ability. 

It is well known that most patients with Parkinson's disease are unable to detoxify from the chemicals to which they are exposed. 

Those unfortunate individuals who have an inherited defect in their detoxification pathways are much more susceptible to the brain-damaging effects of a variety of toxins. 

Glutathione is one of the most important components of the liver's detoxification system. Glutathione therapy is one of the most effective techniques for liver and brain detoxification. 

Treatment with glutathione improves some symptoms of Parkinson's disease, including stiffness, gait, flexibility, coordination, and slurred speech. There was a marked reduction in tremors as well as a reduction in depression. 

Glutathione Therapy for Parkinson's Disease 

The practical problem with increasing glutathione levels is that taking glutathione alone as a dietary supplement does not increase cellular glutathione levels because glutathione is first broken down in the digestive tract to reach cells . 

However, intravenous glutathione therapy and delivery of glutathione precursors are effective in increasing intracellular glutathione levels. Read more about Glutathione Injections in Dubai

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