The nature of glutathione

Glutathione injections is an important physiologically active substance, it is composed of glutamic acid, cysteine ​​and glycine by the condensation of the main tripeptide compound in the skin, it is a widespread active polypeptide. 



Glutathione was isolated from yeast in 1888; In 1921 scientists isolated the crystallized and invented its structure; explaining its chemical structure and synthetic arrangement in 1935, the enzymatic synthesis of glutathione mechanism explored in 1953; continued research into the chemical synthesis of glutathione in the 1970s with the aim of improving the process; With the development of genetic engineering, the supplier of glutathione began to study the production of glutathione bacteria and the (enzymatic) production of immobilized glutathione in the 1980s. 

The relative molecular weight of glutathione is 307.33, the melting point is 189-193 ° C, the crystal was colorless and transparent, the grains are elongated, the isoelectric point is 5.93.It is soluble in water, dilute alcohols, ammonia and dimethylformamide and insoluble in alcohol, ether and acetone. Solid glutathione is more stable, with water in the air, it is easy to oxidize, and the two molecules are also the prototypes of the active oxidative condensation of mercap to glutathione disulfide, that is, glutathione oxide. Expressed in ionic form, it can be seen as the missing oxidation electron (the compound SH is weakly acidic, the group H + SH is).This reaction is reversible, so glutathione acts as a redox. Oxidized glutathione (GSH) and reduced glutathione, which show physiological activity, can play an important physiological role in restoring the function of oxidized glutathione in vivo. Therefore, when glutathione is extracted, substances with strong reducing properties, such as vitamin C, etc., can be added to the solution. If there is a strong reducing material that can protect glutathione, it is not easy to oxidize. 

Glutathione in plants and animals Glutathione occurs naturally in many plants and animals. Very high levels in brewer's yeast, wheat germ and animal liver are 100 = 1000 mg/100 g, 26 = 34 mg/100 g in human blood, in blood with 58 = 73 mg/100 g, in pig blood with 10 = 15 mg/100 g, Tomato, pineapple, cucumber, even higher level (12 = 33 mg/100 g), sweet potato, green bean sprouts, onion, mushrooms, lower level (0.06 = 0.7 mg/100 g). Structure of glutathione containing reactive sulfhydryl-SH, a slightly oxidizing deoxidizer, the specific structure makes an important radical scavenger. The metabolism of many free radicals in the body can damage cell membranes, invade the macromolecules of life, promote aging of the body and produce cancer or induced atherosclerosis. As a cosmetic raw material, glutathione can scavenge free radicals and thus develop a strong anti-aging protective effect. For example, when cells produce a small amount of H2O2 and glutathione, glutathione peroxidase reduces H2O2 to H2O, and in turn is oxidized to GSSG, GSSG by glutathione in liver and red blood cells, glutathione as a catalytic reductase, accepts H, which is reduced to glutathione, to nurture radical reactions. Glutathione is a very special derivative of amino acids and a tripeptide containing a mercapto group, so it plays an important role in vivo. Read more about Best Botox in Dubai

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